Table 2

 Genotypic and allelic frequencies of FAS and FASL in patients and controls and their associations with the risk of lung cancer

GenotypeControls (n = 1270) n (%)Patients (n = 1000) n (%)Crude OR* (95% CI)Adjusted OR† (95% CI)
*Data were calculated by unconditional logistic regression, and †adjusted for sex, age, smoking status, and other genotype where appropriate. OR, odds ratio; CI, confidence interval.
FAS −1377G/A
GG539 (42.5)413 (41.3)1.00 (reference)1.00 (reference)
GA601 (47.3)433 (43.3)0.94 (0.78 to 1.13)0.94 (0.78 to 1.14)
AA130 (10.2)154 (15.4)1.55 (1.17 to 2.04)1.59 (1.21 to 2.10)
A allele frequency0.3390.371
FASL −844T/C
TT109 (8.6)64 (6.4)1.00 (reference)1.00 (reference)
TC560 (44.1)324 (32.4)0.99 (0.69 to 1.40)1.00 (0.71 to 1.42)
CC601 (47.3)612 (61.2)1.73 (1.23 to 2.44)1.79 (1.26 to 2.52)
C allele frequency0.6940.774