Compiled data analysis of the patients and controls
| MMR mutation carrier | Sporadic MSS | Healthy controls | ||||
|---|---|---|---|---|---|---|
| *Age. Beth, Bethesda | ||||||
| All | 167 | 126 | 245 | |||
| Sex | ||||||
| Male | 103 | 74 | 113 | |||
| Female | 64 | 52 | 132 | |||
| MMR gene mutated | ||||||
| MSH2 | 87 | |||||
| MLH1 | 80 | |||||
| Median age, in years, of onset of CRC (range) | 39 (13–62) | 64 (50–94) | 36 (18–65)* | |||
| Criterion | ||||||
| Amsterdam I/II | 99 | |||||
| Beth 2 | 3 | |||||
| Beth 2 and 4 | 6 | |||||
| Beth 2, 3, and 4 | 23 | |||||
| Beth 2, 4, and 7 | 1 | |||||
| Beth 3 and 4 | 14 | |||||
| Beth 3, 4, and 7 | 1 | |||||
| Beth 4 | 16 | |||||
| None | 4 | |||||