Table 1

 Summary of the clinical features of the six affected individuals

Clinical featureA-IV-6A-IV-8A-IV-10A-IV-11B-1B-2
CRMO
    Bone and joint pain++++++
    FeverMildMildMildMildHighHigh
    Radioisotope scan++++++
CDA
    Microcytosis++++++
    Blood transfusionNoNoNoNoFrequentFrequent
    Hb electrophoresisNormalNormalNormalNormalNormalNormal
Skin
    Sweet syndromeYesYesBy reportYesNoNo
    OtherPustulosis
    Relative with psoriasisYesYesYesYesNANA