Results of transmission disequilibrium test in German sporadic inflammatory bowel disease trios stratified for CARD15 genotype
| CARD15 | O/E | p Value* | |
|---|---|---|---|
| *After 10 000 bootstrap replicates. | |||
| CARD15 mutation, + indicates carriers of the R702W, G908R, or 1007insC mutation; − indicates non-carriers. | |||
| O/E, observed/expected 5A allele transmission ratio. | |||
| Crohn’s disease | + | 166/147.49 | 0.0054 |
| − | 170/167.04 | 0.6718 | |
| Stenosis | + | 116/98.56 | 0.0027 |
| − | 100/100.89 | 0.871 | |
| Fistulae | + | 103/84.60 | 0.0007 |
| − | 90/90.39 | 0.942 | |
| Resection | + | 106/89.39 | 0.0023 |
| − | 89/87.87 | 0.8284 | |
| Ileal | + | 147/124.78 | 0.0001 |
| − | 124/124.84 | 0.891 | |
| Right colon | + | 124/109.3 | 0.0115 |
| − | 114/114.84 | 0.8805 | |
| Left colon | + | 57/52.19 | 0.2165 |
| − | 113/113.56 | 0.9206 | |