Table 3

 Summary of confirmed single nucleotide polymorphisms with the confirmed amino acid alterations: acute lung injury

ChrQTLSNP IDGenBankGene nameSNP typeChr positionConf amino acidDescription
Chr  =  mouse chromosome; QTL  =  quantitative trait loci, acute lung injury locus regions; SNP ID  =  specific identification number for the SNP from Celera discovery system; GenBank  =  transcript sequence associated with the gene containing the SNP; Gene name  =  derived from Celera’s annotation; Chr position  =  the base pair position of the SNP on the chromosome according to the Celera database; Conf amino acid  =  confirmed amino acid alteration with the order of A/J mice/C57BL/6J mice; Description  =  description derived from either Celara annotation or GenBank annotation.
Ali1/Ali2/Ali3/Ali4, acute lung injury quantitative trait loci; SNP, single nucleotide polymorphism.
11Ali1mCV24258169AF034955Rad51l3Mis-sense89500890GCC(212)GTCRAD51-like 3 (S cerevisiae)
mCV24260314AF099973Slfn2Mis-sense89693576ATG(207)CTGSchlafen 2
mCV24673293AF081568Tubd1Mis-sense93176928TCA(322)ACATubulin, delta 1
mCV22737741X15313MpoMis-sense94393241GTC(339)ATCMyeloperoxidase
mCV24690994U84389AkapMis-sense95457054ATC(486)ATGA kinase anchor protein
mCV24690995Mis-sense95457493ATC(340)ACC
mCV24691005Mis-sense95457537TTG(325)TTT
mCV24310400AF208663CoilMis-sense95597299TCG(129)TTGCoilin
mCV24318752NM_021213PctpMis-sense96598777ACA(69)GCAPhosphatidylcholine transfer protein
mCV24803224AF152924Stxbp4Mis-sense97142831CAT(494)CGTSyntaxin binding protein 4
mCV24760749BC0162190610040E02RikMis-sense103698905CAA(141)CGARIKEN cDNA 0610040E02 gene
mCV23634907NM_011732Nsep1Mis-sense107548610GCC(5)GCANuclease sensitive element binding protein 1
mCV23222844XM_122319Itga2bMis-sense111166183CTG(944)CCGIntegrin α2b
mCV22581801AK0171194933439F11RikMis-sense111597061GAC(211)GCCRIKEN cDNA 4933439F11 gene
mCV23174311NM_016896Map3k14Mis-sense111945010ACG(486)ATGMitogen activated protein kinase kinase kinase 14
13Ali2mCV24250326BC0135319430025F20RikMis-sense1545145CGT(60)CATRIKEN cDNA 9430025F20 gene
mCV23916243AF291722Skz1-pendingMis-sense18660515ATG(192)GTGSCAN-KRAB-zinc finger gene 1
mCV23280804X59927Fgfr4Mis-sense53228374GTC(735)GCCFibroblast growth factor receptor 4
mCV22736530AF040747Gprk6Mis-sense53508536AGC(417)CGCG protein coupled receptor kinase 6
17Ali3mCV22724951XM_123178XdhMis-sense75214557ATT(241)GTTXanthine dehydrogenase, exon 1
mCV23088765AF022889Ltbp1Mis-sense76300864Latent transforming growth factor binding protein 1
mCV2309085676360387GTG(221)ATG
mCV23089854U19891Cebpa-rs1Mis-sense80240570ACA(875)GCACCAAT/enhancer binding protein α(C/EBP), related sequence 1
6Ali4mCV25192983AJ133125Imap38Mis-sense46253620CGT(151)TGTImmunity associated protein, 38 kDa
mCV24051845U42384Fin15Coding Reg.47711614CAG(35)CGTFibroblast growth factor inducible 15