Summary of confirmed single nucleotide polymorphisms with the confirmed amino acid alterations: acute lung injury
| Chr | QTL | SNP ID | GenBank | Gene name | SNP type | Chr position | Conf amino acid | Description |
|---|---|---|---|---|---|---|---|---|
| Chr = mouse chromosome; QTL = quantitative trait loci, acute lung injury locus regions; SNP ID = specific identification number for the SNP from Celera discovery system; GenBank = transcript sequence associated with the gene containing the SNP; Gene name = derived from Celera’s annotation; Chr position = the base pair position of the SNP on the chromosome according to the Celera database; Conf amino acid = confirmed amino acid alteration with the order of A/J mice/C57BL/6J mice; Description = description derived from either Celara annotation or GenBank annotation. | ||||||||
| Ali1/Ali2/Ali3/Ali4, acute lung injury quantitative trait loci; SNP, single nucleotide polymorphism. | ||||||||
| 11 | Ali1 | mCV24258169 | AF034955 | Rad51l3 | Mis-sense | 89500890 | GCC(212)GTC | RAD51-like 3 (S cerevisiae) |
| mCV24260314 | AF099973 | Slfn2 | Mis-sense | 89693576 | ATG(207)CTG | Schlafen 2 | ||
| mCV24673293 | AF081568 | Tubd1 | Mis-sense | 93176928 | TCA(322)ACA | Tubulin, delta 1 | ||
| mCV22737741 | X15313 | Mpo | Mis-sense | 94393241 | GTC(339)ATC | Myeloperoxidase | ||
| mCV24690994 | U84389 | Akap | Mis-sense | 95457054 | ATC(486)ATG | A kinase anchor protein | ||
| mCV24690995 | Mis-sense | 95457493 | ATC(340)ACC | |||||
| mCV24691005 | Mis-sense | 95457537 | TTG(325)TTT | |||||
| mCV24310400 | AF208663 | Coil | Mis-sense | 95597299 | TCG(129)TTG | Coilin | ||
| mCV24318752 | NM_021213 | Pctp | Mis-sense | 96598777 | ACA(69)GCA | Phosphatidylcholine transfer protein | ||
| mCV24803224 | AF152924 | Stxbp4 | Mis-sense | 97142831 | CAT(494)CGT | Syntaxin binding protein 4 | ||
| mCV24760749 | BC016219 | 0610040E02Rik | Mis-sense | 103698905 | CAA(141)CGA | RIKEN cDNA 0610040E02 gene | ||
| mCV23634907 | NM_011732 | Nsep1 | Mis-sense | 107548610 | GCC(5)GCA | Nuclease sensitive element binding protein 1 | ||
| mCV23222844 | XM_122319 | Itga2b | Mis-sense | 111166183 | CTG(944)CCG | Integrin α2b | ||
| mCV22581801 | AK017119 | 4933439F11Rik | Mis-sense | 111597061 | GAC(211)GCC | RIKEN cDNA 4933439F11 gene | ||
| mCV23174311 | NM_016896 | Map3k14 | Mis-sense | 111945010 | ACG(486)ATG | Mitogen activated protein kinase kinase kinase 14 | ||
| 13 | Ali2 | mCV24250326 | BC013531 | 9430025F20Rik | Mis-sense | 1545145 | CGT(60)CAT | RIKEN cDNA 9430025F20 gene |
| mCV23916243 | AF291722 | Skz1-pending | Mis-sense | 18660515 | ATG(192)GTG | SCAN-KRAB-zinc finger gene 1 | ||
| mCV23280804 | X59927 | Fgfr4 | Mis-sense | 53228374 | GTC(735)GCC | Fibroblast growth factor receptor 4 | ||
| mCV22736530 | AF040747 | Gprk6 | Mis-sense | 53508536 | AGC(417)CGC | G protein coupled receptor kinase 6 | ||
| 17 | Ali3 | mCV22724951 | XM_123178 | Xdh | Mis-sense | 75214557 | ATT(241)GTT | Xanthine dehydrogenase, exon 1 |
| mCV23088765 | AF022889 | Ltbp1 | Mis-sense | 76300864 | Latent transforming growth factor binding protein 1 | |||
| mCV23090856 | 76360387 | GTG(221)ATG | ||||||
| mCV23089854 | U19891 | Cebpa-rs1 | Mis-sense | 80240570 | ACA(875)GCA | CCAAT/enhancer binding protein α(C/EBP), related sequence 1 | ||
| 6 | Ali4 | mCV25192983 | AJ133125 | Imap38 | Mis-sense | 46253620 | CGT(151)TGT | Immunity associated protein, 38 kDa |
| mCV24051845 | U42384 | Fin15 | Coding Reg. | 47711614 | CAG(35)CGT | Fibroblast growth factor inducible 15 | ||