Clinical differential diagnosis of the skin lesions of pseudoxanthoma elasticum
| Feature | Conditions |
|---|---|
| PXE, pseudoxanthoma elasticum. | |
| Papules | Acquired pseudo-PXE related to haemoglobinopathy |
| Skin aging (chronological and/or actinic) | |
| Elastoma, Buschke–Ollendorff syndrome | |
| Pseudo-PXE related to salpeter or D-penicillamine | |
| Papular elastorrhexia | |
| Elastosis perforans serpiginosa | |
| Perforating periumbilical PXE | |
| Plaques or redundant skin | Elastoderma |
| Anetoderma | |
| Cutis laxa | |
| Ehlers–Danlos syndrome (rare) | |