Table 1

FISH results obtained using BAC clones targeting the 16p12.3→16p11.2 interval in two patients carrying 16p partial duplication

RPCI-11 clone name	Cytogenetic localisation	Other region recognised by the probe	FISH signal on normal 16p	FISH signal on dup(16)
RPCI-11 clone name	Cytogenetic localisation	Other region recognised by the probe	FISH signal on normal 16p	Patient 1	Patient 2
The BAC probes in bold target the duplication in both patients
*Additional small and faint signals at 16q22 and 16q24 chromosomal locations.
^†additional small and faint signals at 16p13 and 16q22.
167K14	16p12.3		+	+
429K17	16p12.3		+	+
444F15	16p12.3–12.2		+	+
232I1	16p12.2		+	+
62C15	16p12.2		+	+	+
688G12^†	16p12.2	16p12.2	++	++	++
343H14*	16p12.2	16p11.2	++	+++	+++
98D10*	16p12.2	16p11.2	++	+++	+++
120F20	16p12.2		+	++	++
338J22	16p12.2		+	++
322D12	16p12.2		++	++++
141O15	16p12.2		+	++
21M24	16p12.2		+	++
16A8	16p12.2		+	++
141E3	16p12.2		+	++	++
13G4	16p12.2		+	++
139E11	16p12.2		+	++
450G5	16p12.2		+	++
478K1	16p12.1		+	++
451N20	16p12.1		+	++
417E21	16p12.1		+	++
62O3	16p12.1		+	++
15I10	16p11.2		+	++
24N18	16p11.2	16p12.2	++	++++
28A6	16p11.2		+	++	++
368N21*	16p11.2	16p12.2	++	+++	+++
753J6	16p11.2			+	+
301D18	16p11.2			+
279M12	16p11.2			+
114A4	16p11.2			+	+