Haplotype | NPC patients (2n = 478) | Controls (2n = 572) | OR (95% CI) | p* |
---|---|---|---|---|

The frequencies of haplotypes are indicated in absolute values and percentages in parentheses. Haplotype is constructed based on C-2128T and C-1888T. The sums of genotypes in patients and controls do not add up to the total number of subjects, owing to failure of genotyping for some individuals. *No correction was made for testing multiple alleles. | ||||

T-T | 187 (41.2%) | 292 (53.7%) | 1 | — |

C-T | 57 (12.6%) | 56 (10.3%) | 1.59 (1.05–2.40) | 0.027 |

T-C | 90 (19.8%) | 95 (17.5%) | 1.48 (1.05–2.08) | 0.024 |

C-C | 120 (26.4%) | 101 (18.5%) | 1.86 (1.34–2.56) | 0.00016 |

Total (3 df) | 0.001 |