Test of interaction between ACE I/D genotypes, smoking status, and age
| CHD mortality | CVD mortality | |||
|---|---|---|---|---|
| ID | DD | ID | DD | |
| *Adjusted for gender; †adjusted for age and gender; ‡median age = 68.2 years. | ||||
| Gene-age interaction* | ||||
| p (smokers) | 0.01 | <0.01 | <0.01 | <0.01 |
| p (non-smokers) | 0.75 | 0.58 | 0.63 | 0.15 |
| p (total group) | 0.24 | 0.20 | 0.39 | 0.32 |
| Gene-smoking interaction† | ||||
| p (below median of age)‡ | 0.13 | 0.06 | 0.24 | 0.05 |
| p (above median of age)‡ | 0.46 | 0.83 | 0.65 | 0.98 |
| p (total group) | 0.27 | 0.42 | 0.50 | 0.39 |