Incidence rates of MI and mortality due to CHD and CVD according to ACE I/D genotypes
| A. In smoking groups adjusted for age and gender | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| ACE genotypes | |||||||||
| All | Non-smokers | Smokers | |||||||
| II (n = 1221) | ID (n = 2758) | DD (n = 1558) | II (n = 937) | ID (n = 2113) | DD (n = 1242) | II (n = 284) | ID (n = 645) | DD (n = 316) | |
| Fatal and non-fatal MI | 60 (56) | 69 (131) | 49 (61) | 54 (45) | 69 (100) | 47 (45) | 76 (11) | 54 (31) | 60 (16) |
| CHD mortality | 63 (67) | 58 (151) | 57 (83) | 61 (54) | 57 (120) | 52 (66) | 49 (13) | 55 (31) | 68 (17) |
| CVD mortality | 126 (102) | 122 (243) | 121 (137) | 125 (86) | 117 (192) | 110 (109) | 108 (16) | 130 (51) | 160 (28) |
| B. Gender groups adjusted for age | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| ACE genotypes | |||||||||
| Men | Women | ||||||||
| II (n = 478) | ID (n = 1068) | DD (n = 581) | II (n = 743) | ID (n = 1690) | DD (n = 977) | ||||
| Values are incidence rates per 10 000 person-years (number of events); CHD, coronary heart disease; CVD, cardiovascular disease; MI, myocardial infarction. | |||||||||
| Fatal and non-fatal MI | 82 (33) | 85 (80) | 65 (34) | 33 (23) | 32 (51) | 29 (27) | |||
| CHD mortality | 71 (29) | 66 (64) | 59 (32) | 58 (38) | 52 (87) | 56 (51) | |||
| CVD mortality | 124 (39) | 126 (93) | 120 (50) | 127 (63) | 119 (150) | 122 (87) | |||