Children with multiple meningiomas and other NF2 features or a family history of NF2
| Pt | Sex | Age at Dx/last exam (years) | Number and location of meningiomas | Presenting symptom | Other NF2 features | Family history | Mutation |
|---|---|---|---|---|---|---|---|
| *Deceased. | |||||||
| †Family history in first degree relative of multiple meningiomas. | |||||||
| Patients 1–13 have meningioma(s) plus other disease features of NF2. Patients 19–21 have multiple meningiomas without other disease features of NF2. | |||||||
| Dx, diagnosis; exam, examination; F, female; M, male; NA, data not available; NF2, neurofibromatosis 2; pt, patient. | |||||||
| 1 | M | 9/9 | 1 cranial | Visual loss | Trigeminal schwannoma | None | Not found |
| 2 | M | 7/9 | 1 cranial | Visual loss | 4 cutaneous tumours and hypoglossal schwannoma | None | Not found |
| 4* | M | 9/16† | 4 cranial | Seizures | 4 cutaneous tumours | Mother (patient 3) | Not found |
| 6 | M | 2/6† | 3 cranial | Visual loss | Trigeminal schwannoma (bilateral) | None | Not found |
| 7 | M | 5/8 | 2 cranial | Visual loss | 2 spinal and 3 cutaneous schwannomas | None | 887 del T |
| 8 | M | 9/10 | 1 cranial | Seizures | 3 spinal tumours | None | 58 ins A |
| 10 | M | 7/9 | 2 cranial | Seizures | Cataract | None | 592 C>T |
| 12 | M | 4/4 | 1 cranial | Visual loss | 3rd nerve palsy and 3 cutaneous schwannomas | None | 241–2 G>A |
| 13 | M | 7/8 | 1 cranial | Facial palsy | Facial palsy | None | 443 del C |
| 19 | M | 10 | 2 cranial | NA | NA | None | Not found |
| 20 | M | 15 | 2: optic sheath and falx | NA | NA | None | Not found |
| 21 | M | 13/33 | 2 cranial | NA | None | None | Not found |