Categorical variables in different genotype groups according to gender
| Variable | Leu/Leu | Leu/Val + Val/Val | p Value | G/G | G/C + C/C | p Value |
|---|---|---|---|---|---|---|
| *Eight men and eight women receiving fibrate treatment were excluded. †Percentages of patients with one, two, or three coronary arteries with >50% stenosis. Emboldened p value is statistically significant. n, number; CAD, coronary artery disease. | ||||||
| Women* | n = 225 | n = 26 | n = 157 | n = 88 | ||
| Hypertension | 54.7% | 26.9% | 0.007 | 54.8% | 50.0% | 0.472 |
| Diabetes | 13.8% | 19.2% | 0.459 | 14.2% | 17.0% | 0.552 |
| Smoking | 53.8% | 50.0% | 0.954 | 50.6% | 56.8% | 0.336 |
| Family CAD history | 53.8% | 46.2% | 0.461 | 54.8% | 51.1% | 0.584 |
| Diseased vessels (n)† | 46.7/34.7/18.7% | 53.8/34.6/11.5% | 0.633 | 45.9/36.9/17.2% | 50.0/31.8/18.2% | 0.720 |
| Unstable angina | 28.9% | 38.5% | 0.313 | 28.0% | 34.1% | 0.321 |
| Myocardial infarction | 46.9% | 53.8% | 0.500 | 42.3% | 58.0% | 0.019 |
| Men* | n = 752 | n = 90 | n = 580 | n = 248 | ||
| Hypertension | 43.0% | 36.7% | 0.254 | 42.8% | 40.3% | 0.515 |
| Diabetes | 12.4% | 9.0% | 0.352 | 11.4% | 14.2% | 0.269 |
| Smokers | 81.3% | 76.1% | 0.242 | 81.2% | 79.7% | 0.617 |
| Family CAD history | 46.8% | 51.1% | 0.440 | 54.8% | 51.1% | 0.584 |
| Diseased vessels (n)† | 39.2/33.2/27.5% | 37.8/30.0/32.2% | 0.627 | 39.7/34.0/26.4% | 36.7/30.2/33.1% | 0.145 |
| Unstable angina | 27.9% | 32.2% | 0.393 | 28.8% | 26.2% | 0.448 |
| Myocardial infarction | 56.3% | 52.2% | 0.468 | 54.8% | 58.5% | 0.334 |