Table 2

LOD scores assuming two independent loci contribute to NMTC/goitre

	Cancer multiplicative			Cancer only
	Goitre additive			Multiplicative			Additive
Assume:	19	2		19	2		19	2
	Linked	Linked		Linked	Linked		Linked	Linked
Test:	2	19	Both	2	19	Both	2	19	Both
	Linked	Linked	linked	Linked	Linked	linked	Linked	Linked	linked
103	1.63	1.62	3.21	1.00	1.00	2.05	0.28	0.27	0.93
128	0.48	0.22	0.70	0.48	0.21	0.69	0.24	0.06	0.36
134	−0.00	−0.00	−0.01	−0.01	−0.01	−0.01	−0.00	−0.00	−0.01
188	−0.52	−0.55	−1.07	−0.52	−0.55	−1.06	−0.28	−0.29	−0.45
118	0.45	0.18	0.61	0.20	0.20	0.41	0.09	0.09	0.20
39	0.17	0.17	0.34	0.18	0.18	0.35	0.09	0.09	0.20
86	0.24	−0.52	−0.29	0.23	−0.50	−0.28	0.18	−0.12	0.00
224	−0.71	−0.28	−0.96	−0.80	−0.34	−1.14	−0.30	−0.17	−0.39
201	0.23	0.23	0.46	0.23	0.23	0.46	0.10	0.10	0.23
102	0.37	0.60	0.94	0.47	0.47	0.95	0.17	0.17	0.45
Total	2.33	1.66	3.92	1.47	0.90	2.42	0.56	0.20	1.51
HLOD (α)	2.39 (0.85)	1.78 (0.7)	4.51 (0.7)	1.59 (0.85)	1.06 (0.7)	3.17 (0.7)	0.5 (1.0)	0.21 (0.8)	1.51 (1.0)