Low IQ, autistic disorder, and infantile spasms in TSC2 cases with truncating and non-truncating mutations
| Clinical feature | Total cases | Truncating, 53 cases | Non-truncating, 17 cases | χ2 | p |
|---|---|---|---|---|---|
| IS, infantile spasms. | |||||
| IQ>±70 | 24 | 19 (36%) | 5 (29%) | 0.237 | 0.627 |
| IQ<70 | 46 | 34 (64%) | 12 (71%) | ||
| No autistic disorder | 43 | 33 (62%) | 10 (59%) | 0.064 | 0.800 |
| Autistic disorder | 27 | 20 (38%) | 7 (41%) | ||
| No IS | 29 | 22 (45%) | 7 (44%) | 0.060 | 0.970 |
| IS | 36 | 27 (55%) | 9 (56%) | ||