Table 1

 Sex specific genotype frequencies and fitness estimates

Country of originNNNHHHTotalFitness NNFitness HHAllele frequency N
Healey1–6 are the data published in Healey et al.1
Ishitobi refers to the data published in Ishitobi et al.6
Auranen1,2 are the controls published in Auranen et al.3
The fitness is relative to genotype NH and is computed separately for each sex specific group.
Italics indicate which data came from the original first report.
Females
Healey 1 UK 138 115 13 266 0.86 0.63 0.73
Healey 2 UK 631 493 77 1201 0.94 0.84 0.73
Healey 3 UK 124 94 10 228 0.88 0.64 0.75
Healey 4 Germany 433 373 60 866 0.92 0.81 0.72
Healey 5 Finland 277 152 24 453 1.03 1.11 0.77
Healey 6 UK 590 485 75 1150 0.93 0.81 0.72
Blood donors UK192172253890.890.730.71
Colon cancer controls UK9872181881.101.240.71
Mammography screening control women UK466410819570.970.930.70
Ishitobi Japan955631540.860.430.80
Auranen 1 Australia139123202820.920.800.71
Auranen 2 Australia439322548150.980.940.74
Males
Healey 6 UK 644 435 116 1195 1.15 1.38 0.72
Blood donors UK381329517610.910.780.72
Colon cancer controls UK11595212311.021.050.70