Table 4a

Univariate and multivariable analysis of concerns about genetic testing among HNPCC, FAP, and HBOS syndromes: ability to cope subscale

Ability to cope subscale n ATC score, mean (SD)P value
Cohort
HNPCC3712.45 (3.88)
FAP2611.69 (4.11)
HBOS6712.53 (4.20)0.65*
Age
<40 years5212.61 (4.20)
>40 years7612.22 (4.04)0.59
Gender
Female10512.55 (4.22)
Male2411.58 (3.34)0.29
Disease status
Affected6711.74 (4.05)
Unaffected6312.98 (4.04)0.08
Education
>College8412.57 (4.02)
<College4512.00 (4.20)0.45
Income
<$75 0005212.30 (4.54)
>$75 0007012.31 (3.79)0.99
Partner
No3812.42 (4.16)
Yes9112.35 (4.07)0.93
Individuals with children
No3112.77 (4.12)
Yes9812.24 (4.08)0.53
Risk perception of cancer
High, very high8911.97 (4.59)
Average, low, very low3512.53 (3.97)0.49
Perception of test results
I have an altered gene8411.83 (3.83)
I do not have an altered gene2712.88 (4.08)0.22
Multiple linear regression analysisRegression coefficientP value
*Comparisons post-hoc (HNPCC, P = 0.99; FAP, P = 0.64; Tukey’s test); †the reference group is HBOS.
Intercept12.75
HNPCC†0.010.98
FAP†−0.970.33
Disease status (unaffected)0.150.85
Perception of having an altered cancer gene−0.900.34