Table 3a

Univariate and multivariable analysis of motivations for undergoing genetic testing among HNPCC, FAP, and HBOS syndromes: prevention and medical care subscale

Prevention and medical care subscale n PMC score, mean (SD)P value
Cohort
HNPCC3745.54 (5.71)
FAP2647.80 (6.20)
HBOS6742.53 (8.04)0.004*
Age
<40 years5246.01 (6.47)
>40 years7643.59 (7.65)0.06
Gender
Female10544.14 (7.40)
Male2446.45 (6.28)0.15
Disease status
Affected6743.35 (7.33)
Unaffected6345.60 (7.27)0.08
Education
>College8445.37 (6.43)
<College4544.14 (7.64)0.35
Income
<$75 0005244.80 (6.75)
>$75 0007044.41 (7.76)0.77
Partner
No3845.02 (6.71)
Yes9144.38 (7.48)0.64
Individuals with children
No3146.35 (5.05)
Yes9844.01 (7.74)0.11
Risk perception of cancer
High, very high8945.17 (6.70)
Average, low, very low3544.76 (6.91)0.76
Perception of test results
Have an altered gene8444.07 (7.67)
Do not have an altered gene2746.00 (7.03)0.25
Multiple linear regression analysisRegression coefficientP value
*Comparisons post-hoc (HNPCC, P = 0.10; FAP, P = 0.005; Tukey’s test); †the reference group is HBOS.
Intercept40.84
HNPCC†2.890.05
FAP†5.470.002
Disease status (unaffected)2.840.03
Gender (female)−0.660.69
Age (>40 years)−0.790.58
Individuals with children−0.870.58