Polymorphisms of the PRF1 gene
| Exon | Nucleotide change | Amino acid effect | Allele frequency |
|---|---|---|---|
| 2 | 272 C→T | A91V | 7/202 (3%) |
| 368 G→A | R123H | 1/202 (0.5%) | |
| 435 G→A | V145V | 6/202 (3%) | |
| 462 A→G | A154A | 6/202 (3%) | |
| 519 G→A | T173T | 1/202 (0.5%) | |
| 3 | 755 A→G | N252S | 5/202 (2%) |
| 822 C→T | A274A | 30/202 (15%) | |
| 900 C→T | H300H | 136/202 (67%) |