Table 1

Summary of haplogroup association studies in LHON

StudyControls3460G→A11778G→A14484T→C
ReferenceYearnJNon-JnJNon-JnJNon-JnJNon-J
In most of these studies, haplogroup distribution for a representative sample of normal controls from the local population was also reported. If the latter was not provided, this was sought either directly from the original investigators or from other published sources: Finland9,25 and the Netherlands (Dr G Barbujani, personal communication).
5 19911751615936432
6 199117516159927
26 1992179251743031477532
27 19931751615915123
22 19941601614480816214981
8 199517516159101917413862
28 19976756241323101321147
10 199799792707281117220
29 1997529334963031349
30 19997896920227423211
Current study17925174505936110