Results of the analysis of polymorphisms associated with coronary heart disease or myocardial infarction in prior studies
| Gene | Polymorphism | Common name | P value coronary heart disease unadjusted/adjusted | P value myocardial infarction unadjusted/adjusted | Representative reference |
|---|---|---|---|---|---|
| *one of two single nucleotide polymorphisms that define the E2/E3/E4 haplotypes | |||||
| ABCA1 | ABCA1_1 | R219K | 0.97/0.74 | 0.83/0.25 | 18 |
| ADRA2B | ADRA2B_1 | I/D | 0.84/0.66 | 0.96/0.82 | 19 |
| AGT | AGT_1 | M235T | 0.50/0.93 | 0.45/0.70 | 20 |
| AGTR1 | AGTR1_1 | 1166 A/C | 0.89/0.78 | 0.92/0.95 | 21 |
| APOA1 | APOA1_1 | −75 G/A | 0.05/0.17 | 0.10/0.37 | 22 |
| APOB | APOB_1 | R3611Q | 0.21/0.24 | 0.37/0.28 | 23 |
| APOB | APOB_2 | XbaI | 0.23/0.16 | 0.51/0.24 | 23 |
| APOC3 | APOC3_1 | Sst1 | 0.34/0.98 | 0.12/0.47 | 24 |
| APOE | APOE_1 | * | 0.02/0.03 | 0.02/0.04 | 25 |
| CD14 | CD14_1 | −159 T/C | 0.73/0.54 | 0.94/0.84 | 26 |
| CETP | CETP_4 | Taq1B | 0.28/0.28 | 0.60/0.69 | 27 |
| CYBA | CYBA_1 | H72Y | 0.10/0.54 | 0.08/0.33 | 28 |
| EDN1 | EDN1_2 | 5665 G/T | 0.16/0.58 | 0.43/0.58 | 9 |
| F2 | F2_2 | 20210 G/A | 0.98/0.99 | 0.84/0.61 | 29 |
| F5 | F5_1 | Leiden | 0.51/0.29 | 0.17/0.11 | 30 |
| F7 | F7_2 | R353Q | 0.03/0.06 | 0.05/0.04 | 31 |
| FGB | FGB_3 | −455 G/A | 0.002/0.04 | 0.08/0.23 | 32 |
| GP1BA | GP1BA_1 | T145M | 0.05/0.04 | 0.05/0.05 | 33 |
| HFE | HFE_1 | C282Y | 0.15/0.37 | 0.35/0.39 | 34 |
| IL6 | IL6_1 | −174 G/C | 0.85/0.91 | 0.83/0.78 | 35 |
| ITGB3 | ITGB3_1 | PL-A1/A2 | 0.27/0.07 | 0.21/0.15 | 36 |
| LPL | LPL_1 | HindIII | 0.25/0.50 | 0.47/0.71 | 37 |
| LRP1 | LRP1_5 | 4012 C/T | 0.09/0.06 | 0.14/0.10 | 38 |
| MTHFR | MTHFR_1 | 677 C/T | 0.19/0.10 | 0.07/0.01 | 39 |
| NOS3 | NOS3_1 | D298E | 0.29/0.27 | 0.25/0.29 | 40 |
| PAI1 | PAI1_1 | I/D | 0.71/0.78 | 0.77/0.82 | 41 |
| PON1 | PON1_1 | M55L | 0.69/0.53 | 0.56/0.33 | 42 |
| PPARG | PPARG_2 | 161 C/T | 0.22/0.35 | 0.25/0.55 | 43 |
| SCARB1 | SRB1_2 | HaeIII | 0.87/0.52 | 0.82/0.48 | 44 |
| SELE | SELE_1 | S128R | 0.12/0.17 | 0.06/0.09 | 45 |
| SELP | SELP_1 | T715P | 0.27/0.29 | 0.28/0.46 | 46 |