Table 2

Summary of mutations found in the VEGFR-3 gene

Family	Position	Nucleotide position	Amino acid substitution	Domain	Type of change
PCL-163	Ex 18	2560 G>A	G854S	TK I domain	Missense mutation
PCL-902	Ex 18	2560 G>A	G854S	TK I domain	Missense mutation
PCL-100	Ex 19	2743 G>C	A915P	TK I domain	Missense mutation
PCL-900	Ex 19	2748 C>G	C916W	TK I domain	Missense mutation
PCL-101	Ex 20	2797 G>C	G933R	TK I domain	Missense mutation
PCL-102	Ex 20	2797 G>C	G933R	TK I domain	Missense mutation
PCL-001	Ex 23	3121 C>T	R1041W	TK II domain	Missense mutation
PCL-107	Ex 23	3122 G>A	R1041Q	TK II domain	Missense mutation
PCL-66	Ex 24	nt 3323-3325 del TCT	del F 1108	TK II domain	Deletion
PCL-144	Ex 25	3410 C>T	P1137L	TK II domain	Missense mutation