Distribution of APOE Th1/E47 polymorphism in the Gambia
| Subjects* | Severe malaria | Controls | Total | |||
|---|---|---|---|---|---|---|
| *Percentages within each disease or control group are given in parentheses. | ||||||
| †2×2 χ2 test (df = 1) for comparison with the control group. | ||||||
| ‡3×2 χ2 test (df = 2) for comparison with the control group. | ||||||
| (A) Alleles | ||||||
| Total | 366 | 358 | 724 | |||
| G | 276 | (75.4) | 272 | (76.0) | 548 | (75.7) |
| T | 90 | (24.6) | 86 | (24.0) | 176 | (24.3) |
| χ2† | 0.03 | – | – | |||
| P | 0.87 | – | – | |||
| (B) Genotypes | ||||||
| Total | 183 | 179 | 362 | (56.3) | ||
| G/G | 100 | (54.6) | 104 | (58.1) | 204 | |
| G/T | 76 | (41.5) | 64 | (35.8) | 140 | (38.7) |
| T/T | 7 | (3.8) | 11 | (6.1) | 18 | (5.0) |
| χ2‡ | 1.95 | – | – | |||
| p | 0.38 | – | − | |||