Adjusted relative risk of acute myocardial infarction according to hepatic lipase C-480T genotype status and levels of HDL-C
| HDL-C (mmol/l) | HL C-480T genotype | ||
|---|---|---|---|
| CC (n = 191) | CT, TT (n = 195) | All (n = 386) | |
| Relative risk is adjusted for age, body mass index, smoking, years of hypertension, diabetes, family history of coronary disease, total cholesterol, triglycerides, and energy and fat intake. Total model <0.001; p value for interaction, 0.002. | |||
| CI, confidence interval. *p<0.001; †p = 0.002; ‡ p = 0.008, difference from the highest HDL-C tertile. | |||
| Lowest tertile | 3.992† | 2.426 | 3.378* |
| 95% CI | (1.656–9.627) | (0.923–6.381) | (1.779–6.412) |
| Middle tertile | 3.264‡ | 2.219 | 2.748* |
| 95% CI | (1.358–7.847) | (0.920–5.356) | (1.506–5.017) |
| Highest tertile | 1.0 | 0.968 | 1.0 |
| 95% CI | (0.376–2.488) | ||