Clinical features of study populations
| Japanese | Egyptians | |||||
|---|---|---|---|---|---|---|
| COPD | Control | p | COPD | Control | p | |
| FVC, forced vital capacity; FEV1, forced expiratory volume in one second; NS, not significant. Brinkman’s index: the number of cigarettes/day × the number of years. | ||||||
| Data are presented as the mean (SEM) unless otherwise indicated. | ||||||
| Subjects (n) | 88 | 40 | 106 | 72 | ||
| Sex, M/F (n) | 85/3 | 40/0 | 106/0 | 72/0 | ||
| Age, years | 66.9 (1.6) | 72.9 (1.2) | NS | 62.5 (0.9) | 59.0 (1.0) | NS |
| Brinkman’s index | 1201.6 (70.1) | 1071.1 (66.5 | NS | 1050.0 (60.3) | 990.9 (69.6) | NS |
| FVC % pred | 77.4 (2.2) | 95.9 (3.8) | <0.001 | 56.3 (1.0) | 92.3 (0.9) | <0.001 |
| FEV1 (L) | 1.1 (0.1) | 2.4 (0.1) | <0.001 | 0.9 (0.03) | 2.8 (0.04) | <0.001 |
| FEV1 % pred | 46.7 (1.5) | 91.0 (2.3) | <0.001 | 30.3 (1.1) | 85.9 (0.4) | <0.001 |
| FEV1/FVC, % | 47.1 (1.3) | 85.1 (1.6) | <0.001 | 44.3 (1.2) | 78.3 (1.0) | <0.001 |