Logistic regression model
| Variable | P value | Relative risk | 95% CI | |
|---|---|---|---|---|
| AD, Alzheimer’s disease; CI, confidence interval; DLB, dementia with Lewy bodies. | ||||
| *APOE ϵ2/– analysis was not carried out because there were no patients with DLB who had an ϵ2 allele. | ||||
| AD compared with controls | ||||
| Age | 0.053 | 1.03 | 1.00–1.06 | |
| Sex | 0.092 | 1.60 | 0.93–2.77 | |
| APOE ϵ4/− | 0.000 | 5.50 | 2.33–12.99 | |
| APOE ϵ3/− | 0.239 | 1.60 | 0.73–3.47 | |
| APOE ϵ2/− | 0.026 | 0.43 | 0.21–0.90 | |
| 16189C | 0.546 | 0.77 | 0.33–1.79 | |
| Length heteroplasmy | 0.104 | 2.22 | 0.85–5.81 | |
| DLB compared with controls* | ||||
| Age | 0.128 | 1.03 | 0.99–1.06 | |
| Sex | 0.144 | 0.64 | 0.35–1.17 | |
| APOE ϵ4/− | 0.002 | 4.43 | 1.74–11.31 | |
| APOE ϵ3/− | 0.546 | 1.29 | 0.57–2.93 | |
| 16189C | 0.997 | 1.00 | 0.40–2.50 | |
| Length heteroplasmy | 0.867 | 0.92 | 0.34–2.47 | |