Table 7

 Tests for association of type 2 diabetes with SNP alleles (or haplotypes at compound loci)

LocusHaplotypeAdjusted for age, sex onlyAdjusted for age, sex, admixture
ScoreObs Info% InfoORpScoreObs Info% InfoORp
For haplotypes where the observed information is less than 1, p values are omitted.
Candidate genes
CAPN10 UCSNP 43-19-63-44
CAPN10G-3-C-T0.4239.87941.010.950.5238.13921.010.93
CAPN10G-2-T-T6.1426.56961.260.234.2324.45921.190.39
CAPN10G-2-C-T6.0425.5921.270.236.8424.05901.330.16
CAPN10G-2-C-C−6.8021.26970.730.14−6.3220.05940.730.16
CAPN10A-3-C-T−5.0336.9960.870.41−4.5535.20930.880.44
CAPN10Others−0.780.48−0.710.46
PPARG E6-Pro12Ala
PPARGC-Ala1.255.493931.260.590.735.57851.140.76
PPARGC-Pro−8.7824.44990.700.08−7.7423.26930.720.11
PPARGT-Ala5.2017.38971.350.214.3414.90901.340.26
PPARGT-Pro2.322.576902.460.152.672.50732.910.09
ABCC8/KCNJ11 E31-E33-E23K
ABCC8/KCNJ11A-T-G13.9644.06961.370.0311.2839.25901.330.07
ABCC8/KCNJ11G-T-G1.52546.18961.030.822.54941.77921.060.69
ABCC8/KCNJ11G-G-A−16.649.821000.720.02−14.8745.83950.720.02
ABCC8/KCNJ11Others1.1160.49661.040.5004
ABCC8-ex16−7.6052.1099.80.860.29−4.9547.6695.40.900.47
GNB3−6.6041.461000.850.31−6.3139.69980.850.32