Pairwise linkage disequilibrium of polymorphisms in A2M and OLR1
| A2M-UTR | A2M-12e | A2M-15i | A2M-18i | OLR1 | |
|---|---|---|---|---|---|
| For a key to A2M polymorphisms see Saunders et al4. | |||||
| Cells above the diagonal represent D′-values, and cells below the diagonal represent P values (Fisher’s exact test, two-sided: “NS” indicates P>0.05; **indicates P⩽0.01; ***indicates P⩽0.001). LD statistics calculated with “2by2” (http://linkage.rockefeller.edu/ott/linkutil.htm), based on haplotype frequencies in one affected individual per pedigree estimated by the FBAT program. | |||||
| A2M -UTR | – | 0.72 | 1 | 0.94 | 0.02 |
| A2M -12e | *** | – | 0.86 | 0.78 | 0.11 |
| A2M -15i | *** | ** | – | 1 | 0.05 |
| A2M -18i | *** | *** | *** | – | 0.06 |
| OLR1 | NS | NS | NS | NS | – |