TF C2 and HFE C282Y and H63D genotypes in AD, in MCI, and in controls
| Genotypes | AD | MCI | Controls | |||
|---|---|---|---|---|---|---|
| % | (n) | % | (n) | % | (n) | |
| AD, Alzheimer’s disease; TF and HFE, the transferrin and haemochromatosis genes, respectively; MCI, mild cognitive impairment. | ||||||
| TF C2-negative | 57.6 | (110) | 71.0 | (49) | 66.5 | (179) |
| TF C2 heterozygotes | 34.0 | (65) | 24.6 | (17) | 25.7 | (69) |
| TF C2 homozygotes | 8.4 | (16) | 4.3 | (3) | 7.8 | (21) |
| HFE C282Y-negative | 84.3 | (161) | 75.4 | (52) | 88.1 | (237) |
| HFE C282Y heterozygotes | 15.7 | (30) | 23.2 | (16) | 11.5 | (31) |
| HFE C282Y homozygotes | 0 | (0) | 1.4 | (1) | 0.4 | (1) |
| HFE H63D-negative | 72.2 | (138) | 75.4 | (52) | 72.1 | (194) |
| HFE H63D heterozygotes | 26.2 | (50) | 24.6 | (17) | 24.9 | (67) |
| HFE H63D homozygotes | 1.6 | (3) | 0 | (0) | 3.0 | (8) |
| Total number | (191) | (69) | (269) | |||