Problems in infancy in 85 patients with Mulibrey nanism
| Feature | Frequency (%) |
|---|---|
| Neonatal problems | |
| Respiratory problems | 31 |
| Ventilatory assistance needed | 20 |
| Cyanosis while crying | 15 |
| Feeding difficulties | 30 |
| Nasogastric feeding tube needed | 17 |
| Suspicion of hydrocephalus | 6 |
| Suspicion of sepsis | 6 |
| Cardiac arrhythmia | 1 |
| Growth failure | 96 |
| Infections | |
| Upper respiratory infections >4/year | 51 |
| Pneumonia | 47 |
| Necessitating hospital care | 30 |
| Three or more pneumonias | 27 |
| Ventilatory assistance needed | 25 |
| Intubation needed | 14 |
| Middle ear infections >4/year | 38 |
| Feeding difficulties | 50 |
| Vomiting | 39 |
| Difficulties in sucking | 31 |
| Nasogastric feeding tube needed | 31 |
| Delay in switching to solid foods | 24 |
| Fatigue during eating | 21 |
| Percutaneous gastrostomy needed | 6 |
| Muscular hypotonicity | 46 |
| Suspicion of hydrocephalus | 16 |
| Hypoglycaemia | 15 |
| Congestive heart failure | 11 |
| Resuscitation during first year of life | 11 |
| Due to infection | 9 |
| Due to aspiration | 1 |
| Due to arrhythmia | 1 |
| Death during infancy | 5 |
| Due to infection | 2.5 |
| Due to congestive heart failure | 2.5 |