Sequence analysis of suspected cases of LHON not harbouring one of the three primary pathogenic LHON mtDNA mutations (G11778A, T14484C, or G3460A)
| Patient No | Changes from reference sequence |
|---|---|
| Bold, unique changes not previously reported. All of these changes were synonymous. | |
| 1 | C3107del; T4216C; A4769G; A4917G; G5147A; G9947A; C10175T; T10463C; A11251G; G11719A; A11812G; T12441C; G13368A; A13563G; T13743C; A14233G; C14766T; G14905A; A15326G |
| 2 | C3107del; T3197C; A4769G; A11467G; G11719A; A12308G; G12372A; T13617C; T14182C; C14766T; A15326G |
| 3 | C3107del; A4769G; C9911T; G13759A; A15326G |
| 4 | C3107del; A4769G; A10771G; A15326G |
| 5 | C3107del; A4769G; A13098G; T14956C; A15326G |
| 6 | C3107del; T4733C; A4769G; G13708A; A15052G; A15326G |
| 7 | C3107del; G4580A; A4769G; A15326G |
| 8 | C3107del; A3720G; A4769G; A5390G; T5426C; A10876G; A11467G; G11719A; A12308G; G12618A; G12372A; T13020C; T13734C; C14766T; A15326G |
| 9 | C3107del; T3197C; A4769G; T5495C; A11467G; G11719A; A12308G; G12372A; A12612G; T13617C; C14766T; A14793G; A15218G; A15326G |
| 10 | C3107del; T4216C; A4769G; A10398G; A11251G; G11719A; G13708A; G14323A; C14766T; T14798C; C15199T; A15326G |