TDT | S-TDT | Combined scores | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|

Allele | Trans | Untrans | χ^{2} | p value | Y | Mean (A) | Var (V) | Z′ | p value | Z′ | p value |

Y, total observed numbers of the allele among affected sibs; A, mean of the numbers of the allele among affected sibs; V, variance of the allele among affected sibs; Z′, the correction of the Z score. | |||||||||||

In combined scores, Z′ is Bonferroni’s correction value. | |||||||||||

3 | 39 | 17 | 8.643 | <0.01 | 204 | 186.8 48 | 47.814 | 2.408 | <0.05 | 3.517 | <0.01 |

Non-3 | 17 | 39 | 8.643 | <0.01 | 84 | 71.429 | 20.601 | 2.660 | <0.05 | 0.182 | >0.05 |