Table 6

TDT/S-TDT results for alleles of microsatellite D8S261

TDTS-TDTCombined scores
AlleleTransUntransχ2p valueYMean (A)Var (V)Z′p valueZ′p value
Y, total observed numbers of the allele among affected sibs; A, mean of the numbers of the allele among affected sibs; V, variance of the allele among affected sibs; Z′, the correction of the Z score.
In combined scores, Z′ is Bonferroni’s correction value.
339178.643<0.01204186.8 4847.8142.408<0.053.517<0.01
Non-317398.643<0.018471.42920.6012.660<0.050.182>0.05