Clinical features of a cohort of 33 patients with Cohen syndrome
| Patient | Age at assessment (y) | Sex | Ethnic origin | OFC centile | Height centile | Weight centile | Body Mass Index centile | Neutrophil count (×10−9/mm3) | Myopia | Retinopathy |
|---|---|---|---|---|---|---|---|---|---|---|
| *Patients are from a known consanguineous family. | ||||||||||
| *1 | 16 | F | Arabic | <<0.4 | <<0.4 | <0.4 | 25 | 2.2 | Low | Y |
| *2 | 15 | M | Arabic | 0.4 | 0.4 | 25 | 75 | 1.7 | Low | Y |
| 3 | 15 | M | UK | <<0.4 | 0.4 | 25 | 91 | 1.1 | High | Y |
| 4 | 7 | M | UK | <<0.4 | 25 | 25 | >25 | 2.0 | High | Y |
| 5 | 7 | F | UK | 0.4 | 25 | 75 | >91 | 1.2 | High | Y |
| 6 | 16 | F | UK | <<0.4 | <<0.4 | 5 | >50 | 0.7 | Low | Y |
| 7 | 7 | F | UK | <<0.4 | <0.4 | 3 | 75 | 0.6 | Low | Y |
| 8 | 4 | F | UK | 10 | 10 | 75 | >91 | 0.3 | High | Y |
| 9 | 21 | F | UK | <3 | 0.4 | >90 | >98 | 0.5 | High | Y |
| 10 | 3 | F | UK | <<0.4 | <3 | <3 | 25 | 0.7 | High | Y |
| 11 | 46 | F | UK | <3 | 10 | 90 | >91 | 0.6 | High | Y |
| 12 | 17 | M | UK | <3 | <<0.4 | 0.4 | – | <1.5 | Y | Y |
| 13 | 7 | M | UK | <<0.4 | 3 | 10 | >50 | 0.9 | High | Y |
| 14 | 6 | M | UK | <<0.4 | 10 | 25 | >91 | 0.6 | High | Y |
| 15 | 9 | M | UK | 0.4 | 25 | 75 | 75 | – | Y | Y |
| 16 | 15 | M | UK | 3 | 25 | 75 | >91 | 0.7 | High | Y |
| 17 | 18 | M | UK | <0.4 | 25 | >90 | >91 | 1.1 | High | Y |
| 18 | 26 | M | Dutch | <3 | <3 | 10 | 50 | 0.7 | High | Y |
| 19 | 32 | M | Dutch | 25 | 10 | >90 | >98 | 0.9 | High | Y |
| 20 | 5 | M | UK | 0.4 | 0.4 | 25 | >91 | 0.6 | Low | Y |
| *21 | 28 | F | UK | 0.4 | 0.4 | 98 | >98 | 1.1 | Y | – |
| *22 | 15 | F | UK | 0.4 | 10 | 75 | 91 | 1.8 | High | – |
| *23 | 22 | F | UK | 0.4 | 0.4 | 25 | 50 | 1.4 | Y | – |
| 24 | 3 | M | UK | <0.4 | 0.4 | 10 | >75 | <1.5 | Y | Y |
| 25 | 4 | F | UK | 0.4 | 0.4 | 50 | >98 | <1.5 | High | Y |
| 26 | 15 | M | UK | 3 | 0.4 | 10 | >75 | 0.8 | High | Y |
| 27 | 15 | F | UK | <3 | 0.4 | 25 | >75 | 0.9 | Low | Y |
| 28 | 8 | F | UK | <3 | 0.4 | 25 | >75 | 0.5 | N | Y |
| *29 | 6 | F | Arabic | – | <3 | 50 | >91 | Normal | High | Y |
| *30 | 10 | F | Arabic | – | 10 | 50 | >75 | Normal | High | Y |
| *31 | 12 | M | Arabic | 10 | 10 | 75 | >75 | Normal | High | Y |
| 32 | 42 | M | UK | <3 | <0.4 | 75 | >98 | 0.7 | High | Y |
| 33 | 34 | M | UK | 0.4 | <<0.4 | 50 | >98 | 0.6 | Y | Y |