Table 3

Number of cases in each final carrier risk class, broken down by original (cancer based) risk class, including both HBOC and HNPCC family members.

Final carrier risk
Cancer based carrier risk0%Low25%50%100%Total
The off diagonal values (bold) comprise the 2906 cases of change in carrier risk status as a result of mutation test result disclosure. Note that of the 441 classified as cancer based risk=final risk=100, 265 were tested or inferred carriers based on mutation test results, while in the remaining 176 cases’ final risk was based on cancer status only.
50%550001608 297 2455
100%2200 0 441463
Total223734202575188978910 910