Allele and genotype frequencies for the G to T transition at position −159 in the promoter region of the CD14 gene
| Coeliac patients | |||
|---|---|---|---|
| Base | HLA-DQ2 or DQ-8 n=115) | Neither HLA-DQ2 nor DQ-8 (n= 37) | Healthy controls (n=180) |
| *Allelic frequency (Fisher’s exact test): typical v atypical HLA coeliac patients: p=0.320; typical HLA coeliac patients v healthy controls: p=0.500; atypical HLA coeliac patients v healthy controls: p=0.581. | |||
| §Genotype frequency (3×2 contingency tables): typical v atypical HLA coeliac patients: χ2=1.13, p=0.567; typical HLA coeliac patients v healthy controls: χ2=1.61, p=0.446; atypical HLA coeliac patients v healthy controls: χ2=0.62, p=0.733. | |||
| *C | 0.53 | 0.46 | 0.50 |
| 123/230 | 34/74 | 181/360 | |
| T | 0.47 | 0.54 | 0.50 |
| 107/230 | 40/74 | 179/360 | |
| §C/C | 0.33 | 0.24 | 0.27 |
| 38/115 | 9/37 | 48/180 | |
| C/T | 0.41 | 0.43 | 0.47 |
| 47/115 | 16/37 | 85/180 | |
| T/T | 0.26 | 0.33 | 0.26 |
| 30/115 | 12/37 | 47/180 | |