A comparison of the HHT1 and HHT2 groups looking at the presence or absence of disease features
| Feature | Endoglin mutation | ALK1 mutation | Significance |
|---|---|---|---|
| Epistaxis | 48/49 | 34/34 | NS |
| Telangiectasis | 47/49 | 28/34 | NS |
| Pulmonary arteriovenous malformation (PAVM) | 17/49 | 0/34 | p<0.001 |
| Cerebral arteriovenous malformation (CAVM) | 4/49 | 1/34 | NS |
| Gastrointestinal haemorrhage | 6/49 | 9/34 | NS |
| Gastrointestinal haemorrhage (age 60+) | 1/9 | 7/19 | NS |
| Miscarriage in affected female (age 16+) | 8/28 | 8/20 | NS |
| Symptoms suggestive of classical migraine | 20/49 | 6/34 | NS |