Table 3

Comparison of clinical features and the size of the 22q13 deletion, using linear regression to obtain a coefficient of correlation. Measures used for developmental assessment include the Scales of Independent Behaviour (SIB) and the Developmental Profile II (DPII). Number of patients indicates the number of patients for whom data was available in that category. AE - age equivalent

Clinical feature	Coefficient of correlation	Significance   F	No of patients
SIB Broad Independence	0.406	0.075	20
SIB Broad Independence Age Equivalent	0.526	0.017	20
SIB Motor Skills AE	0.397	0.083	20
SIB Social/Communication AE	0.400	0.080	20
SIB Personal Living Skills AE	0.569	0.009	20
SIB Community Living Skills AE	0.546	0.013	20
DPII Physical Skills	0.374	0.127	18
DPII Self Help	0.495	0.037	18
DPII Social Skills	0.217	0.387	18
DPII Academic Skills	0.310	0.210	18
DPII Communication Skills	0.266	0.285	18
DPII Estimated Intelligence Score	0.173	0.491	18
Words spoken	0.169	0.371	30
Words recognised	0.072	0.825	12
Hypotonia	0.368	0.018	41
Ability to walk	0.384	0.095	20
Growth	0.160	0.357	35
Head circumference	0.322	0.059	35
Organ malformations	0.247	0.159	34
Neurological scan abnormalities	0.120	0.659	16
Seizures	0.038	0.825	36
Hearing defects	0.186	0.286	35
Chewing behaviour	0.191	0.311	30
High pain tolerance	0.299	0.214	31
Fleshy hands	0.053	0.761	35
Abnormal toenails	0.132	0.451	35
Syndactlyly	0.069	0.695	35
Clinodactyly	0.145	0.407	35
Large hands	0.288	0.093	35
Recurrent ear infections	0.389	0.025	33
Caesarean section	0.136	0.450	33
Respiratory problems at birth	0.278	0.110	34
Epicanthic folds	0.114	0.514	35
Ptosis	0.297	0.084	35
Deep set eyes	0.253	0.142	35
Long eyelashes	0.019	0.915	35
Full eyelids	0.112	0.522	35
Preauricular pits/tags	0.195	0.246	37
Dysmorphic ears	0.063	0.710	37
Abnormal ears	0.092	0.586	37
Long ears	0.121	0.475	37
High palate	0.198	0.260	34
Pointed chin	0.501	0.004	31
Dental anomalies	0.400	0.019	34
Full cheeks	0.135	0.477	30
Bulbous nose	0.010	0.958	31
Wide nasal bridge	0.193	0.274	34
Long philtrum	0.073	0.690	32
Dolichocephaly	0.267	0.140	32
Recurrent upper respiratory problems	0.293	0.087	35