Level of OLR1 mRNA in lymphocytes from AD cases and elderly controls according to the 3′-UTR polymorphisms
| Level of ORL1 mRNA (arbitrary units) | No | Controls | No | AD cases |
|---|---|---|---|---|
| *AD cases versus controls: p=0.009. | ||||
| †AD cases versus controls: p=NS. | ||||
| ‡AD cases versus controls: p=0.009. | ||||
| Whole population | 39 | 1.67 (0.40 to 7.03) | 20 | 0.61 (0.13 to 2.81)* |
| +1073 C/T genotype | ||||
| TT | 9 | 0.94 (0.21 to 4.16) | 5 | 0.90 (0.12 to 2.81)† |
| CC+CT | 25 | 1.96 (0.43 to 8.91) | 15 | 0.53 (0.13 to 2.14)‡ |
| 3′-UTR T/A genotype | ||||
| TT | 24 | 1.72 (0.34 to 8.79) | 18 | 0.66 (0.14 to 3.24)† |
| AT | 10 | 1.39 (0.39 to 4.98) | 2 | 0.29 (0.17 to 0.48)† |