Relevant data concerning pre-test probability models
| Entry criteria | No of pedigrees | BRCA1 mutation prevalence | BRCA2 mutation prevalence | Population | Designation | Reference |
|---|---|---|---|---|---|---|
| At least 3 breast/ovarian cancer | 102 | 18% | 12% | Spanish | HCSC | (12) |
| At least 3 breast/ovarian cancer | 148 | 10.8% | 8.8% | Finnish | HUCH | (13) |
| At least 3 breast/ovarian cancer | 164 | 13.4% | 7.3% | Dutch | LUMC | (14) |
| Women attending clinics | 169 | 16% | Not analysed | White North-American | U Penn | (9) |
| Not applicable | 4716 | 9.2% | 5.9% | White North-American | Frank 2002 | (10) |