Table 4

Multivariable models: odd ratios (OR) and 95% confidence intervals (95% CI) of criteria from logistic regression models

ModelsCriteriaCriteriaOR95% CIp value
*Relatives diagnosed with breast cancer at age ⩽35 and ovarian cancer at age ⩽60.
BRCA1 model
1First degree relative with diagnosis age restriction*4.701.30 to 17.010.02
3Proband diagnosed age ⩽353.411.04 to 11.120.04
4Second or third degree relatives with diagnosis age restriction*5.191.66 to 16.240.005
11Ashkenazi Jewish background4.461.18 to 16.880.03
BRCA2 model
2Second degree relatives4.081.12 to 14.840.03
7Multiple primary tumours6.481.90 to 22.090.003
11Ashkenazi Jewish background3.901.07 to 14.160.04