Table 2

BRCA1 and BRCA2 mutations

CasesExonNucleotideChangeTypeBICEthnicity
BIC, Breast Cancer Information Core; AJ, Ashkenazi Jewish descent.
BRCA1
    12185insAInsertionYesWhite
    22185delAGDeletionYesAJ
    32185delAGDeletionYesAJ
    42185delAGDeletionYesAJ
    52185delAGDeletionYesAJ
    68613insTInsertionYesWhite
    711970ins7InsertionNoWhite
    8111292del40DeletionYesWhite
    9111806C-TNonsenseYesWhite
    10112457C-TNonsenseYesWhite
    11113450DelCAAGDeletionYesWhite
    12113636ins154InsertionNoWhite
    13113867G-TNonsenseYesWhite
    14144603G-TNonsenseYesWhite
    15154728C-TNonsenseNoWhite
    16185255G-ANonsenseYesWhite
    17205382insCInsertionYesWhite
BRCA2
    18101179insAInsertionYesWhite
    19112157delGDeletionYesWhite
    20113036delACAADeletionYesWhite
    21113036delACAADeletionYesWhite
    22114304delCDeletionYesWhite
    23115117C-GNonsenseYesWhite
    24115910C-GNonsenseYesWhite
    25116174delTDeletionYesAJ
    26116174delTDeletionYesAJ
    27116174delTDeletionYesAJ
    28116174delTDeletionYesAJ
    29116503delTTDeletionYesWhite
    30229132delCDeletionYesWhite
    31249481insAInsertionYesWhite