MALF | ||||||||
---|---|---|---|---|---|---|---|---|

0 | 1 | |||||||

Variable | Tissue | Procedure | Value | Level of trisomy | Absence of malformation | Presence of malformation | Risk | Statistic, RR and p value |

dCVS | Cytotrophoblast | Direct CVS | 1 | 100% | 23 | 19 | 45% | Fisher exact test, RR = ∞, p = 0.015 |

0 | <100% | 8 | 0 | 0% | ||||

AF | Amniotic fluid | Amniocentesis | 1 | >0% | 15 | 37 | 71% | Yates chi-square = 13.90, RR = 2.10, p = 0.0002 |

0 | 0% | 39 | 20 | 34% |