Associations with BW*
| Variable | Tissue | Procedure | Value | Level of trisomy | No | Mean BW* | SD | t statistic, df, and p value |
|---|---|---|---|---|---|---|---|---|
| *Weight of the fetus/neonate in terms of the number of SDs from gestational age corrected general population mean birth weights.14 | ||||||||
| dCVS | Cytotrophoblast | Direct CVS | 1 | 100% | 34 | −2.05 | 1.19 | t = 2.22, df = 36, p = 0.016 |
| 0 | <100% | 4 | −0.52 | 2.20 | ||||
| cCVS | Chorionic villous stroma | Cultured CVS | 1 | 100% | 31 | −1.80 | 1.10 | t = 1.91, df = 34, p = 0.032 |
| 0 | <100% | 5 | −0.71 | 1.70 | ||||
| AF | Amniotic fluid | Amniocentesis | 1 | >0% | 22 | −2.82 | 1.07 | t = 3.55, df = 68, p = 0.0003 |
| 0 | 0% | 48 | −1.67 | 1.33 | ||||
| AMN | Amniotic mesenchyme | Postnatal or necropsy sampling | 1 | >0% | 7 | −3.13 | 0.87 | t = 2.66, df = 16, p = 0.009 |
| of amnion followed by culture | 0 | 0% | 11 | −1.48 | 1.48 | |||