TP53 R72P genotypes by age of diagnosis of breast cancer and BRCA1/2 mutation status
| TP53 genotype | Median age | (IQR) | p value |
|---|---|---|---|
| Three women in the sample set had both a BRCA1 and a BRCA2 mutation. | |||
| BRCA1 or BRCA2 mutation | |||
| R/R (n=26) | 42 | (35–51) | 0.01 |
| P/* (n=13) | 32 | (30–38) | |
| BRCA1 mutation | |||
| R/R (n=19) | 46 | (35–51) | 0.05 |
| P/* (n=8) | 32 | (30–41.5) | |
| BRCA2 mutation | |||
| R/R (n=9) | 39 | (35–46) | 0.39 |
| P/* (n=6) | 35 | (30–43) | |
| No detectable mutation | |||
| R/R (n=60) | 49 | (37–61.5) | 0.98 |
| P/* (n=28) | 50 | (42.5–57) | |