Counsellees offered further diagnostics when information on cousins was excluded and included from the risk assessment. The numbers of pedigrees that met one of the inclusion criteria are given in the second column
| No of pedigrees (%) | Threshold | Risk assessment including or excluding cousins | No of counsellees referred (%) | No of mutation carriers among referred counsellees (%) | |
|---|---|---|---|---|---|
| Small pedigree | 81 749 (1.6%) | 20% | Exclusive | 12 304 (15.1) | 3607 (29.3) |
| Inclusive | 12 396 (15.2) | 3667 (29.6) | |||
| 30% | Exclusive | 4982 (6.1) | 1914 (38.4) | ||
| Inclusive | 5084 (6.2) | 1975 (38.8) | |||
| Large pedigree | 97 074 (1.9%) | 20% | Exclusive | 19 997 (20.6) | 5977 (29.9) |
| Inclusive | 20 138 (20.7) | 6177 (30.7) | |||
| 30% | Exclusive | 7701 (7.9) | 3230 (41.9) | ||
| Inclusive | 8551 (8.8) | 3630 (42.5) | |||
| Age + 10 | 124 912 (2.5%) | 20% | Exclusive | 16 804 (13.5) | 5233 (31.1) |
| Inclusive | 17 501 (14.0) | 5545 (31.7) | |||
| 30% | Exclusive | 9535 (7.6) | 3624 (38.0) | ||
| Inclusive | 10 293 (8.2) | 3979 (38.7) |