No of pedigrees (%) | Threshold | Risk assessment including or excluding cousins | No of counsellees referred (%) | No of mutation carriers among referred counsellees (%) | |
---|---|---|---|---|---|
Small pedigree | 81 749 (1.6%) | 20% | Exclusive | 12 304 (15.1) | 3607 (29.3) |
Inclusive | 12 396 (15.2) | 3667 (29.6) | |||
30% | Exclusive | 4982 (6.1) | 1914 (38.4) | ||
Inclusive | 5084 (6.2) | 1975 (38.8) | |||
Large pedigree | 97 074 (1.9%) | 20% | Exclusive | 19 997 (20.6) | 5977 (29.9) |
Inclusive | 20 138 (20.7) | 6177 (30.7) | |||
30% | Exclusive | 7701 (7.9) | 3230 (41.9) | ||
Inclusive | 8551 (8.8) | 3630 (42.5) | |||
Age + 10 | 124 912 (2.5%) | 20% | Exclusive | 16 804 (13.5) | 5233 (31.1) |
Inclusive | 17 501 (14.0) | 5545 (31.7) | |||
30% | Exclusive | 9535 (7.6) | 3624 (38.0) | ||
Inclusive | 10 293 (8.2) | 3979 (38.7) |