Table 2

Genotype combinations and haplotypes of (IL1A SNP +4845, IL1B SNP +3954, and IL1RN VNTR) in skin prick test negative (SPT−) and skin prick test positive (SPT+) patients. IL1A SNP +4845 (allele 1 is G, allele 2 is T), IL1B SNP +3954 (allele 1 is C, allele 2 is T), IL1RN VNTR (IVS2, 86 bp dup 2–5). Genotype combinations containing 1.1, 1.2 and 2.2 (but not 1.3) are presented

Genotype combinationsAllSPT−SPT+
IL1AIL1BIL1RNNo%No%No%OR (95% CI)
No=number of patients (in genotype combination)/chromosomes (in haplotypes), CI=confidence intervals.
1.11.11.17218.94318.22920.11.13 (0.670 to 1.910)
1.21.11.1184.7114.774.91.05 (0.396 to 2.760)
1.11.21.130.800.032.1
1.21.21.16918.25121.61812.5 0.52 (0.289 to 0.928)
2.21.21.1143.783.464.21.24 (0.421 to 3.650)
1.22.21.120.520.800.0
2.22.21.1225.8145.985.60.93 (0.381 to 2.280)
1.11.11.26717.63916.52819.41.22 (0.713 to 2.090)
1.21.11.2195.0145.953.50.57 (0.201 to 1.620)
2.21.11.220.520.800.0
1.11.21.230.820.810.70.82 (0.074 to 9.110)
1.21.21.24612.12912.31711.80.96 (0.505 to 1.810)
2.21.21.230.831.300.0
1.12.21.210.310.400.0
1.22.21.210.300.010.7
2.22.21.241.131.310.70.54 (0.056 to 5.270)
1.11.12.2266.883.41812.5 4.07 (1.720 to 9.630)
1.21.12.271.852.121.40.651 (0.294 to 8.030)
2.21.22.210.310.400.0
Haplotypes
11132741.020641.812140.30.94 (0.701 to 1.260)
1 1 2 180 22.9 92 18.7 88 29.3 1.80 (1.290 to 2.530)
22118022.812224.85819.30.73 (0.511 to 1.030)
211445.7275.4175.81.03 (0.554 to 1.930)
2 1 2 24 2.9 21 4.2 3 1.0 0.227 (0.0670 to 0.766)
113141.881.662.01.23 (0.424 to 3.590)
222101.281.620.060.41 (0.085 to 1.920)
12191.150.941.31.32 (0.351 to 4.940)