Characteristics of the 75 PCGP families analysed for RNASEL mutations. Criteria used to describe evidence for prostate cancer linkage to 1q24-25 markers are described in the Material and methods
| No of families | No of family members with prostate cancer | No of African American families | |
|---|---|---|---|
| *All affected family members from three of these families were sequenced for RNASEL mutations. | |||
| Families with high evidence for linkage to 1q24-25 | 19 | 3.1 ± 0.6 | 4 |
| Families with moderate evidence for linkage to 1q24-25 markers | 11 | 5.6 ± 3.8 | 8 |
| Families with low evidence for linkage to 1q24-25 markers | 9 | 4.4 ± 1.6 | 4 |
| Families with no linkage data* | 36 | 5.3 ± 2.3 | 0 |
| Total | 75 | 4.7 ± 2.4 | 16 |