Table 16

Comparison of frequencies of phenotypic features in CO and FS

Physical findingRef 2 (n=124)Ref 3 (n=63)Our series (n=117)
CO85%93%88%
Unilateral25%24.8%
Bilateral57%47.9%
Unstated10%
Extended hair growth34%34.2%
Facial asymmetry10%5.1%
Ear abnormalities84%44%59%
Atresia/stenosis eam15%17.9%
Nasal abnormalities85%37%
Cleft lip and palate11%7%11.1%
Renal abnormalities37%
Renal agenesis84%37%45.3%
Bladder abn10%17%
Cystic dysplasia3%12%
Abnormal genitalia80%49%
Indeterminate sex6%5.1%
Abnormalities in females 54%
Clitoral hypertrophy39%36.8%
Bicornuate uterus14%8.8%
Vaginal atresia14%12.3%
Cystic ovaries11%
Rudimentary uterus4%8.8%
Abnormalities in males 41%
Cryptorchidism24%31.5%
Micropenis21%14.8%
Hypospadias3%9.3%
Syndactyly79%54%61.5%
Laryngeal atresia83%21%30.8%
Lung hypoplasia7%11.1%
Anal stenosis/atresia6%16.2%
Talipes6%10.2%
Congenital heart disease6%12%
Umbilical hernia28%12%6%
Umbilicus displaced6%11.1%