Table 1

Summary of FISH results of analysis of translocation breakpoints using unique and whole chromosome painting probes in carriers of balanced translocations

TranslocationChromosomeProbeLocusDistance from the telomere (Mb)Hybridisation signal on chromosome
+/- faint hybridisation signal seen on the prometaphase chromosomes, + presence of hybridisation signals, - absence of hybridisation signals.
der(4)der(13)
t(4;13)(p16.3;q34)4pWHCRD4S961.5++
815h5D4S30324.2-5++
WCP4Chromosome 4++
13q785d7D13S1150.78-+
929f12D13S13151.2-+
WCP13Chromosome 13+/-+
der(2)der(7)
t(2;7)(q37;q36)2q770a05D2S1970.673++
854c09D2S33812++
847e04D2S23483.5-4.5++
WCP2Chromosome 2++/-
7qOncorD7S2470.006++
79g3 VIPR2 2.69++
942g09D7S637/D7S24473.5++
WCP 7Chromosome 7++
der(7)der(10)
t(7;10)(q36;q26)7qOncorD7S2470.006++
965c12D7S5501.9++
942g09D7S637/D7S24473.5++
WCP7Chromosome 7++
10q907b06D10S15610.7-2.3++
WCP10Chromosome 10+/-+