Table 1

Summary of FISH results of analysis of translocation breakpoints using unique and whole chromosome painting probes in carriers of balanced translocations

Translocation	Chromosome	Probe	Locus	Distance from the telomere (Mb)	Hybridisation signal on chromosome
+/- faint hybridisation signal seen on the prometaphase chromosomes, + presence of hybridisation signals, - absence of hybridisation signals.
					der(4)	der(13)
t(4;13)(p16.3;q34)	4p	WHCR	D4S96	1.5	+	+
		815h5	D4S3032	4.2-5	+	+
		WCP4	Chromosome 4		+	+
	13q	785d7	D13S115	0.78	-	+
		929f12	D13S1315	1.2	-	+
		WCP13	Chromosome 13		+/-	+
					der(2)	der(7)
t(2;7)(q37;q36)	2q	770a05	D2S197	0.673	+	+
		854c09	D2S3381	2	+	+
		847e04	D2S2348	3.5-4.5	+	+
		WCP2	Chromosome 2		+	+/-
	7q	Oncor	D7S247	0.006	+	+
		79g3	VIPR2	2.69	+	+
		942g09	D7S637/D7S2447	3.5	+	+
		WCP 7	Chromosome 7		+	+
					der(7)	der(10)
t(7;10)(q36;q26)	7q	Oncor	D7S247	0.006	+	+
		965c12	D7S550	1.9	+	+
		942g09	D7S637/D7S2447	3.5	+	+
		WCP7	Chromosome 7		+	+
	10q	907b06	D10S1561	0.7-2.3	+	+
		WCP10	Chromosome 10		+/-	+