Significance of clinical covariates for patients with AA or with AG or GG genotype of ACE A2350G polymorphism by Cox proportional hazard model
| Covariate | p Value | Hazard ratio (95% CI) |
|---|---|---|
| CI, confidence interval; ACEi, angiotensin I converting enzyme inhibitor; ARB, angiotensin receptor blocker. | ||
| Patients with the AA genotype of ACE A2350G | ||
| Urinary protein excretion>1.0 g/day | 0.0147 | 2.620 (1.209 to 5.680) |
| Hypertension | 0.0007 | 3.846 (1.766 to 8.377) |
| No administration of ACEi or ARB | <0.0001 | 7.473 (2.899 to 19.265) |
| Patients with the AG or GG genotype of ACE A2350G | ||
| Urinary protein excretion >1.0 g/day | 0.0059 | 3.307 (1.412 to 7.743) |
| Hypertension | 0.0120 | 2.381 (1.210 to 4.689) |
| No administration of ACEi or ARB | 0.1119 | 1.767 (0.876 to 3.567) |