Distribution of haptoglobin genotypes
Genotype | Total (n=109) | Pre-eclampsia (n=25) | PE + HELLP (n=84) | Controls (n=166) |
---|---|---|---|---|
Percentages are given in parentheses. | ||||
Genotypes: Hp1-1: both alleles encoding for α1. Hp1-2: one allele encoding for α1 and the other for α2. Hp2-2: both alleles encoding for α2. Hp0-0: no amplification of one of the alleles. | ||||
Hp2-2 | 30 (28%) | 6 (24%) | 24 (29%) | 58 (35%) |
Hp2-1 | 53 (49%) | 12 (48%) | 41 (49%) | 73 (44%) |
Hp1-1 | 25 (23%) | 7 (28%) | 18 (21%) | 35 (21%) |
Hp0-0 | 1 (1%) | 1 (1%) | ||
Frequency of Hp2 allele | 0.53 | 0.48 | 0.55 | 0.57 |